Diabetes is no longer considered life threatening, nonetheless diabetes and complications due to diabetes, when not under control, remain to be sixth leading cause of death having a higher mortality rate than some cancers such as prostate cancer, breast cancer and colon cancer. Diabetic foot ulcer occurs when an ulcer or a wound develop in an area in the lower legs or feet which do not heal or are difficult to treat leading to the exposure of the underlying tissue and becoming susceptible to infections.. Symptoms and Rating It is not uncommon for people with diabetes to have diabetic foot ulcers for some time without being aware of the development. Due to nerve damage and loss of sensations and the ability to feel pain, foot damage, even from such simple things as pressure from shoes or a small cut, go unnoticed and unprotected resulting in worsening skin loss, blisters and a possibility of a serious infection than may progress in a matter of days.
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In statements to the press in Havana, the director of the Genetic Engineering and Biotechnology Center CIGB Doctor Luis Herrera underscored the advantages of the medication produced by his entity, known as Heberprot-P, which has been administered to more than Cuban patients, with successful results and full response by 87 of the cases. Doctor Ernesto Lopez, head of the CIGB commercial division, explained that Heberprot-P is and injectable formula that steps up the cicatrization of deep and complex ulcers, thus reducing the number of amputations.
Doctor Lopez said that the medication has been registered in Cuba and included in the basic medications program; it has been patented in South Africa, Australia and Singapore. There are , diabetic patients in Cuba, 12, of whom may be suffering from diabetic foot ulcers, while the number of amputations could reach up to 1,, the doctor explained.
With that in mind, said the specialist, Cuba is creating all conditions and training personnel to administer Heberprot-P throughout the country including primary medical attention. Doctor Perez added that the medication will be available to all patients suffering from diabetic food ulcers. Heberprot-P, a medication produced by Cuban biotechnology, reduces the number of surgical operations, cicatrization time, possible complications like gangrene and infections, and avoids high costs derived from long-time hospitalization; it also improves quality of life and the functional recovery of patients.
Doctor Jorge Berlanga, also from the CIGB, explained that 85 percent of amputations can be prevented, while 70 percent of those surgeries are applied on patients suffering from diabetes, a disease affecting some million people around the world. Follow up post 1 added on June 03, by publisher with total posts Imagine when the US and Cuba can cooperate on biotechnology. Follow up post 2 added on August 29, by danborges There is an error in your citation of the Agencia Cubana de Noticias press release.
This means that roughly patients out of the patients treated with Herberprot-P showed a full successful response to the treatment. Follow up post 3 added on October 26, by Evey Loyo Can you tell me how to get ahold of some of this medication? I am afflicted with a foot ulcer and I think that I could benefit from the treatment. I have been laying in bed for over 1 month and I am still not fully healed. Thank you for your reply. Follow up post 5 added on October 29, by Michele Organ Would like to know if you can get this in Canada.
I understand that it is very costly in the USA. I hope that this information helps you. Hasta la victoria siempre, Nick Follow up post 8 added on November 17, by yangzhenli hello I am a chinese man. PLS contact me.
Heberprot-P: a novel product for treating advanced diabetic foot ulcer.
Epidermal growth factor FRE , human recombinant h. Pharmacokinetic profiles of the applied I-FCEhrec, its effect to the organs and ways of elimination were the subjects of analyses. The studies on rats and dogs were done by one application of the medicine, in the usual way or in the endovenous one. The highest levels, expressed in the equivalent ng per a gram of tissues rose to kidneys, liver, skin and stomach.
Heberprot-P: a novel product for treating advanced diabetic foot ulcer. Diabetic foot ulcer is a principal diabetic complication. It has been shown that diabetic patients have decreased growth factor concentrations in their tissues, particularly epidermal growth factor. Growth factor shortage impairs wound healing, which leads to chronic nonhealing wounds and sometimes eventual amputation.
Symptoms and Rating
The basic principles of its functioning were based on the research of U. These bacteria and yeasts can fabricate complex molecules of great therapeutic value at an attractive cost, and within a very brief time period," the Cuban researcher explained. Epidermal growth factor EGF was among the first molecules cloned in our country through genetic engineering, achieving the addition of silver sulfadiazine, used in treating burns. By , Cuban researcher Jorge Berlanga, a member of the biomedical wound healing team at the CIGB, developed a model in rats to study the use of epidermal growth factor in the management of neuropathy, one of the complications of diabetes.