ANEMIA PERNISIOSA PDF

Diagnosis Bagaimana anemia pernisiosa didiagnosis? Untuk mendiagnosis anemia pernisiosa dokter akan menanyakan riwayat kesehatan Anda dan juga keluarga. Ada kemungkinan anemia bisa didapatkan dari warisan alias turun temurun. Selain itu, dokter akan melakukan pemeriksaan fisik. Selama pemeriksaan fisik, dokter Anda dapat memeriksa kulit pucat atau kekuningan karena pembesaran hati.

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B deficiency vs. Pernicious anemia is strictly an autoimmune disorder. It results from a lack of IF and poor B absorption. This vitamin deficiency can be treated by altering your diet or adding a B supplement or B injection to your healthcare regimen.

In people with B deficiencies or regular anemia, the body can absorb B On the other hand, someone with pernicious anemia struggles to do so. Pernicious anemia is also seen in children who are born with a genetic defect that prevents them from making IF. Some individuals are more likely than others to develop pernicious anemia.

Your doctor will usually need to do several tests to diagnose you with pernicious anemia. These include: Complete blood count. This test measures vitamin B and iron levels in blood serum.

Vitamin B deficiency test: Your doctor can assess your vitamin B levels through a blood test. Low levels indicate a deficiency. Your doctor may also want to see if there has been any damage to your stomach walls. They can diagnose this through a biopsy. The cells are then examined microscopically for any damage.

IF deficiency test. Intrinsic factor deficiency is tested through a blood sample. In a healthy immune system, antibodies are responsible for finding bacteria or viruses. They then mark the invading germs for destruction. In this case, the antibodies destroy the cells making IF. The treatment for pernicious anemia is a two-part process. Your doctor will treat any existing vitamin B deficiency and check for iron deficiency.

Treatment begins with: vitamin B injections that are slowly decreased over time complete blood counts to measure vitamin B and iron levels in blood serum blood tests to monitor replacement treatments Vitamin B injections can be given daily or weekly until the B levels return to normal or close to normal. During the first few weeks of treatment, your doctor may recommend limiting physical activity.

You can administer the shots yourself or have someone else give them to you at home to save you trips to the doctor. After your B levels are normal, your doctor may recommend you take regular doses of B supplements instead of the injection. These come in pills, nasal gels, and sprays. Complications Your doctor may want to monitor you on a long-term basis. This will help them identify possible serious effects of pernicious anemia. The most dangerous complication is gastric cancer.

They can check for the start of cancer at regular visits and through biopsies. Other potential complications of pernicious anemia include: nerve damage memory problems, confusion, or other neurological symptoms heart damage.

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Anemia perniciosa: sintomas, tratamentos e causas

Untreated, it can lead to neurological complications, and in serious cases, death. Many of the signs and symptoms are due to anemia itself, when anemia is present. Causes[ edit ] Vitamin B12 cannot be produced by the human body, and must be obtained from the diet. When foods containing B12 are eaten, the vitamin is usually bound to protein and is released by proteases released by the pancreas in the small bowel. Following its release, most B12 is absorbed by the body in the small bowel ileum after binding to a protein known as intrinsic factor.

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